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Gellerich et al

In addition to SSTR2, PRRT has been extended to other receptors, such as the gastrin-releasing peptide (GRP) and cholecystokinin-2 (CCK-2) receptors

Importantly, nuclear-localized FOXO4-positive Leydig cells in elderly testes showed reduced expression of 3-HSD, a rate-limiting enzyme in testosterone synthesis, implying a connection between nuclear FOXO4 and age-related decline in testosterone production [1]

E., Zwerger, M., Ung, W

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